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The host range of a viral mutualist is tied to factors that regulate gene expression

Read the full article on ScienceDirect. Permissiveness of lepidopteran hosts is linked to differential expression of bracovirus genes Text by Michael Strand Polydnaviruses in the genus Bracovirus are large double-stranded DNA viruses that have evolved a mutualistic (beneficial) association with a group of insects called parasitoid wasps. These wasps fully rely on bracoviruses to parasitize…






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Study suggests: Antiviral RISC that targets longer RNAs may help plants avoid damaging its own mRNAs

Read the full article on ScienceDirect. An in vitro reprogrammable antiviral RISC with size-preferential ribonuclease activity Text by Herman Scholthof   It has been recognized now for about 15 years that plants, like other eukaryotes, have evolved a defense mechanism to target and destroy virus RNA to combat the infection. The components of the silencing pathway are…






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New insights into the structure of multi-component virus populations in a host

Read the full article on ScienceDirect. Intra-host structure of multi-genotype populations of a plant RNA virus assessed by a novel RNA in situ hybridization approach Text by Svetlana Folimonova and María Bergua    Citrus tristeza virus (CTV) represents a peculiar, somewhat unique, virus model. It has been known since long time that field populations of…






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A novel immuno-modulatory role of Nsp2TF of porcine reproductive and respiratory syndrome virus in down-regulation of SLA-I expression

Read the full article on ScienceDirect. The non-structural protein Nsp2TF of porcine reproductive and respiratory syndrome virus down-regulates the expression of Swine Leukocyte Antigen class I Text by Qian M. Cao, Sakthivel Subramaniam, and X.J. Meng Porcine reproductive and respiratory syndrome virus (PRRSV), an arterivirus, circulates in pig farms worldwide causing immense economic losses to…






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Unexpected picornavirus diversity in a single diarrhoeic chicken

Read the full article on ScienceDirect. Complete genome analysis of avian picornaviruses representing up to six genera Text by Ákos Boros In this project our aim was to gain detailed insight into the enteric picornavirus diversity of a single diarrheic chicken introduced recently to a novel location. During the course of our investigation the complete…






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Identification of Structural and Morphogenesis Genes of Pseudoalteromonas phage RIO-1 and Placement within the Evolutionary History of Podoviridae

Read the full article on ScienceDirect. HMM–HMM comparisons find homologous virion proteins across diverse phages Text by Stephen C. Hardies and Byung Cheol Cho   Pseudoalteromonas phage φRIO1 is a marine bacteriophage isolated as part of a project to improve the understanding of the diversity of phages in the marine ecosystem. Initial characterization indicated that…






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Intriguing novel influenza viruses derived from bats

Read the full article on ScienceDirect Characterization of the glycoproteins of bat-derived influenza viruses Text by Junki Maruyama   In 2012 and 2013, papers reported novel influenza viruses detected from bats. The bat-derived influenza viruses (BatIVs) are genetically distinct from other known influenza A viruses (IAVs), and thus have been categorized into the new subtypes.…






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Herpes Simplex Virus sequencing shows stability in the genomes and variability in the technology

Read the full article on ScienceDirect This research article is dedicated to the late Priscilla Shaffer Text by Robin Colgrove   Though well-known to those slogging deep in the genome-sequencing trenches, less-appreciated aspects of NextGen sequencing merit wider exposure among general audiences. Technological advances have made “easy” sequences, well, easy -and rendered “difficult” sequences doable-…